Table 4.
| Table 4a. Estrogen use among women study participants | ||
|---|---|---|
| ERT USED | No ERT | |
| Age | 63.97 (9.98) years | 74.4 (13.4) years |
| Education | 11.6 (4.6) years | 7.1 (8.4) years |
| AD | 19 (5%) | 361 (95%) |
| Unaffected | 77 (21%) | 289 (79%) |
| Table 4b. Estrogen use, APOE genotype and risk of AD among women study participants | ||||||
|---|---|---|---|---|---|---|
| ε4 | ERT | Number at Risk | AD | OR* | 95%CI | Significance |
| − | − | 348 | 178 (51.1%) | 1.0 | -- | Reference |
| − | + | 53 | 5 (9.4%) | 0.2 | 0.1–0.5 | p = 0.002 |
| + | − | 305 | 185 (60.7%) | 1.9 | 1.3–2.9 | p < 0.001 |
| + | + | 43 | 14 (32.6%) | 0.8 | 0.3–1.8 | p = 0.533 |
Differences are statistically significant, p<0.001
= adjusted for age and education