Table 5.

Comparison of participants with and without history of ERT

	No ERT (n=653)	ERT (n=96)	Significance*
Head injury	7.2%	6.3%	p=.760
Smoking	29.1%	26.0%	p=.531
Alcohol use	1.5%	3.1%	p=.229
Hypertension	51.2%	47.4%	p=.489
Diabetes	17.1%	10.4%	p=.096
Myocardial infarction	4.7%	2.1%	p=.414
Pulmonary disease	6.1%	7.4%	p=.624
Thyroid disease	5.6%	9.6%	p=.135
Liver disease	5.9%	8.4%	p=.345
Renal insufficiency	1.1%	0%	p=.604
Stroke	7.1%	2.2%	p=.076
Seizure	1.9%	1.1%	p=1.000
Cancer	3.4%	3.9%	p=1.000
Arthritis	31.0%	32.6%	p=.753
APOE ε4**	46.7%	44.8%	p=.725

ERT = postmenopausal estrogen replacement therapy; percentages reflect those positive for each risk factor;

^*= Corrected for multiple comparisons using Bonferroni method (for α = .05, corrected significance level = .05/17 = .003). P-values in bold denote significant differences at the p<.003 significance level;

^**= homozygous or heterozygous for ε4 allele