Table I.
Relative composition of oligosaccharides (%)a | |||||||
---|---|---|---|---|---|---|---|
Antibody | G0 | G1 | G2 | G0F | G1F | G2F | Fu(−)b |
Nonfucosylated anti-CD20 | 64.0 | 33.0 | 3.0 | n.d.c | n.d. | n.d. | 100 |
Fucosylated anti-CD20 | n.d. | n.d. | n.d. | 41.9 | 51.1 | 7.0 | n.d. |
Rituximab | n.d. | n.d. | n.d. | 55.1 | 40.8 | 4.1 | n.d. |
aEach composition value reflects the relative amount in the total complex- type oligosaccharides detected.
bRelative amount of nonfucosylated oligosaccharides.
cn.d.: not detected (less than 2.0%).