Table 2.

Primary and secondary outcomes at 6 and 12 months and between-group differences

	Exercise		Usual care		Mean differencea	95% CI of mean difference	Adjusted mean differenceb	95% CI of adjusted mean difference	P-value
	Mean	SD	Mean	SD
Outcomes at 6 months
MLwHFQc	36.26	24.08	34.49	23.98	0.25	−5.03 to 5.53	−2.53	−7.87 to 2.80	0.3
Distance on ISWT/m	226.95	120.3	206.18	135.2	21.18	−5.79 to 48.12	14.98	−11.89 to 41.86	0.1
Self-reported physical activityd	4.63	3.54	3.54	3.81	1.14*	0.05 to 2.23	1.05	−0.05 to 2.14	0.06
HADS anxiety score	6.39	4.34	5.45	4.23	0.57	−0.42 to 1.56	0.45	−0.55 to 1.45	0.4
HADS depression score	6.51	4.07	5.90	3.78	−0.57	−1.52 to 0.39	−0.68	−1.64 to 0.28	0.2
EQ-5Dd	0.663	0.242	0.617	0.319	0.064	−0.01 to 0.14	0.11*	0.04 to 0.18	0.004
Systolic BP	122.66	16.62	126.91	21.03	0.30	−4.92 to 5.52	−0.30	−5.52 to 4.94	0.9
Diastolic BP	70.86	11.50	69.62	14.11	2.07	−1.06 to 5.19	1.94	−1.17 to 5.06	0.2
Outcomes at 12 months
MLwHFQc	37.61	20.97	34.91	24.80	2.23	5.99 to 16.81	−0.55	−5.87 to 4.76	0.8
Self-reported physical activityd	3.60	2.64	3.78	4.09	−0.12	−1.11 to 0.86	0.05	−1.1 to 0.96	0.9
HADS anxiety score	6.68	4.31	5.62	4.50	0.75	−0.28 to 1.79	0.23	−0.81 to 1.27	0.7
HADS depression score	6.26	3.73	5.50	3.91	−0.98*	−1.90 to −0.06	−1.07*	−2.00 to −0.14	0.02
EQ-5Dd	0.679	0.21	0.691	0.28	0.059	−0.003 to 0.121	0.058	−0.01 to 0.12	0.07

BP, blood pressure; HADS, Hospital Anxiety and Depression Scale; ISWT, incremental shuttle walking test; MLwHFQ, Minnesota Living with Heart Failure Questionnaire.

^aAdjusted for baseline value.

^bAdjusted for baseline value, age, sex, NYHA class, centre of recruitment, presence or absence of AF, HADS, and blood pressure at baseline.

^cScores range from 0 to 121, with higher scores indicating worse quality of life.

^dSelf-reported physical activity using score on 0–18 scale.

^eScores range from 1.00 (indicating perfect health) to –0.59 (worse imaginable health state).

*P < 0.05.