Table 1.

Key exclusion criteria for patients in the Karolinska-Rennes (KaRen) study

(1) Evidence of primary hypertrophic or restrictive cardiomyopathy or systemic illness known to be associated with infiltrative heart disease

(2) Known cause of right heart failure (HF) not related to left ventricular (LV) dysfunction

(3) Pericardial constriction

(4) Clinically significant pulmonary disease as evidenced by requirement of current home oxygen

(5) End-stage renal disease currently requiring dialysis

(6) Bi-ventricular pacemaker (cardiac resynchronization therapy) (patients who have a conventional pacemaker may be included)

(7) Anticipated or indication for cardiac surgery (patients who have indication for surgery but may not undergo surgery because of some contraindication, for example age, may not be included)

(8) Anticipated percutaneous intervention on aortic stenosis (patients who undergo other percutaneous intervention, for example percutaneous coronary intervention, may be included)