Table 1.
Genotype and allele frequency distributions of Ngb polymorphisms
| Ngb polymorphism | All | Male | Female | ||||||
| Controls n (%) |
LVD n (%) |
SVD n (%) |
Controls n (%) |
LVD n (%) |
SVD n (%) |
Controls n (%) |
LVD n (%) |
SVD n (%) |
|
| 89+104 c>t | |||||||||
| cc | 23(14.6) | 92(41.6) | 52(38.8) | 14(13.6) | 67(41.9) | 27(35.5) | 9(16.4) | 25(41.0) | 25(43.1) |
| ct | 85(53.8) | 97(43.9) | 56(41.8) | 67(65.0) | 66(41.3) | 34(44.7) | 18(32.7) | 31(50.8) | 22(37.9) |
| tt | 50(31.6) | 32(14.5) ** | 26(19.4) ** | 22(21.4) | 27(16.8) ** | 15(19.8)** | 28(50.9) | 5(8.2)** | 11(19.0)** |
| c | 131(41.5) | 281(63.6) | 160(59.7) | 95(46.1) | 200(62.5) | 88(57.9) | 36(32.7) | 81(66.4) | 72(62.1) |
| t | 185(58.5) | 161(36.4)** | 108(40.3)** | 111(53.9) | 120(37.5)** | 64(42.1)* | 74(67.3) | 41(33.6)** | 44(37.9)** |
| H-W | 0.173 | 0.437 | 0.128 | ||||||
| 322-110 (6a)>5a | |||||||||
| 6a6a | 39(24.7) | 53(24.0) | 32(23.9) | 25(24.3) | 39(24.4) | 18(23.7) | 14(25.5) | 14(23.0) | 14(24.1) |
| 6a5a | 88(55.7) | 118(53.4) | 63(47.0) | 58(56.3) | 81(50.6) | 38(50.0) | 30(54.5) | 37(60.7) | 25(43.1) |
| 5a5a | 31(19.6) | 50(22.6) | 39(29.1) | 20(19.4) | 40(25.0) | 20(26.3) | 11(20.0) | 10(16.4) | 19(32.8) |
| 6a | 166(52.5) | 224(50.7) | 127(47.4) | 108(52.4) | 159(49.7) | 74(48.7) | 58(52.7) | 65(53.3) | 53(45.7) |
| 5a | 150(47.5) | 218(49.3) | 141(52.6) | 98(47.6) | 161(50.3) | 78(51.3) | 52(47.3) | 57(46.7) | 63(54.3) |
| H-W | 0.142 | 0.312 | 0.508 | ||||||
| Ngb polymorphism | ≤ 60 years | >60years | |||||||
| Controls n (%) |
LVD n (%) |
SVD n (%) |
Controls n (%) |
LVD n (%) |
SVD n (%) |
||||
| 89+104 c>t | |||||||||
| cc | 13(18.8) | 26(38.2) | 15(41.7) | 10(11.2) | 66(43.1) | 37(37.8) | |||
| ct | 37(53.6) | 32(47.1) | 15(41.7) | 48(53.9) | 65(42.5) | 41(41.8) | |||
| tt | 19(27.5) | 10(14.7)* | 6(16.6)* | 31(34.9) | 22(14.4)** | 20(20.4)** | |||
| c | 63(45.7) | 84(61.8) | 45(62.5) | 68(38.2) | 197(64.4) | 115(58.7) | |||
| t | 75(54.3) | 52(38.2)* | 27(37.5)* | 110(61.8) | 109(35.6)** | 81(41.3)** | |||
| 322-110 (6a)>5a | |||||||||
| 6a6a | 18(26.1) | 16(23.5) | 15(41.7) | 21(23.6) | 37(24.2) | 17(17.3) | |||
| 6a5a | 36(52.2) | 40(58.8) | 14(38.9) | 52(58.4) | 78(51.0) | 49(50.0) | |||
| 5a5a | 15(21.7) | 12(17.6) | 7(19.4) | 16(18.0) | 38(24.8) | 32(32.7) | |||
| 6a | 72(52.2) | 72(52.9) | 44(61.1) | 94(52.8) | 152(49.7) | 83(42.3) | |||
| 5a | 66(47.8) | 64(47.1) | 28(38.9) | 84(47.2) | 154(50.3) | 113(57.7) | |||
Compared with control group: *P < 0.05, **P < 0.01
H-W indicates Pearson's P value for χ2 test of Hardy-Weinberg equilibrium.