Table 4.
Association study with Ngb haplotypes in LVD and SVD patients
| Haplotype Poly1/Poly2 | LVD vs Control | SVD vs Control | ||||||
| LVD n (%) |
Control n (%) |
OR (95%CI) | P | SVD n (%) |
Control n (%) |
OR (95%CI) | P | |
| c-6a | 131.91(29.8) | 62.48(19.8) | 1.726(1.224–2.434) | 0.002 | 64.59(24.1) | 62.48(19.8) | 1.288(0.869–1.910) | 0.201 |
| c-5a | 149.09(33.7) | 68.52(21.7) | 1.838(1.318–2.563) | <0.0001 | 95.42(35.6) | 68.52(21.7) | 1.997(1.384–2.880) | <0.0001 |
| t-6a | 92.09(20.8) | 103.53(32.8) | 0.540(0.389–0.750) | <0.0001 | 62.42(23.3) | 103.53(32.8) | 0.623(0.431–0.900) | 0.011 |
| t-5a | 68.91(15.6) | 81.47(25.8) | 0.532(0.371–-0.762) | 0.001 | 45.58(17.0) | 81.47(25.8) | 0.590(0.393–0.886) | 0.010 |
| Global χ2 | 36.407 | 20.966 | ||||||
| Fisher P | <0.0001 | <0.0001 | ||||||
Poly1: 89+104 c>t; Poly2: 322-110 (6a)>5a