Table 2.
RCAS1 immunoreactivity in pharyngeal and laryngeal cancer and clear surgical margin derived from the same individuals.
| RCAS1 immunoreactivity | |||||
|---|---|---|---|---|---|
| Variables | Number | - | +1 | +2 | +3 |
| Pharyngeal and laryngeal squamous cell carcinoma | 51 | 0 | 0 | 22 (44%) | 29 (56%) |
| Clear surgical margin | 51 | 1 (3.5%) |
24 (44.5%)* | 25 (48.5%)* | 1 (3.5%) |
*The change in the intensity of immunoreactivity was observed in six specimens (12%), in one case in the group of the +1 RCAS1 immunoreactivity and in 5 cases in the group of +2 RCAS1 immunoreactivity; the expression decreased with the distance from cancer cells. In four examined samples, the RCAS1 immunoreactivity level in closely tumor-adjacent tissue was established as moderate and decreasing to weak in the line of resection. In two cases, weak RCAS1 immunoreactivity in the directly tumor-adjacent tissue diminished to the point of absence in the resection line.