Table 3.
Intensities of the peaks per day of sample preparation, category of sample storage duration and age group in healthy controls
| M/z 4276 | M/z 4292 | M/z 8129 | M/z 8941 | ||
| n | Median intensity (IQR) | Median intensity (IQR) | Median intensity (IQR) | Median intensity (IQR) | |
| Day of sample preparation | |||||
| Day 1 | 24 | 74.04 (47.56–103.27) |
62.78 (45.17–79.91) |
27.39 (22.79–29.62) |
78.94 (45.96–84.49) |
| Day 2 | 24 | 24.83 (9.58–38.24) |
34.61 (28.54–39.32) |
22.65 (18.02–26.89) |
72.85 (50.43–105.05) |
| p-value* | 48 | <0.001 | 0.001 | 0.008 | 0.853 |
|
Sample storage duration (months) |
|||||
| ≤ 11 | 13 | 75.81 (33.59–118.06) |
63.48 (37.10–79.58) |
27.54 (21.94–31.63) |
57.48 (43.11–79.66) |
| 12–17 | 11 | 72.28 (50.60–87.56) |
62.11 (46.25–83.88) |
27.24 (24.70–29.87) |
81.30 (52.43–99.14) |
| 18–31 | 12 | 32.33 (12.37–40.50) |
33.99 (25.21–45.65) |
23.66 (15.58–27.08) |
62.97 (42.67–111.06) |
| ≥ 32 | 12 | 16.43 (8.38–35.85) |
34.77 (29.84–37.99) |
22.18 (20.46–26.89) |
73.47 (52.76–105.05) |
| p-value# | 48 | 0.001 | 0.011 | 0.063 | 0.620 |
| p-trend† | 48 | <0.001 | 0.003 | 0.032 | 0.423 |
| Age (yrs) | |||||
| < 49.3 | 16 | 45.26 (19.00–77.58) |
46.38 (31.02–62.95) |
25.15 (21.29–27.55) |
73.84 (49.50–84.49) |
| 49.3–57.5 | 16 | 19.79 (8.38–62.11) |
35.78 (28.52–63.14) |
24.90 (21.98–27.62) |
69.16 (39.17–85.8) |
| > 57.5 | 16 | 45.90 (23.58–85.81) |
40.01 (30.47–72.05) |
27.12 (20.43–33.59) |
76.15 (56.15–101.64) |
| p-value# | 48 | 0.346 | 0.680 | 0.753 | 0.850 |
| p-trend† | 48 | 0.583 | 0.940 | 0.438 | 0.880 |
M/z = Mass to Charge ratio, IQR = Inter-Quartile Range, * Mann-Whitney U Test, # Kruskal Wallis Test, † Jonckheere-Terpstra Test