Table 7.
Description of the peaks found in the different studies
Protein 1 | Protein 2 | Protein 3 | ||||
Li et al. (2002) [3] | kDa | 4.3 ↓ | 8.1 ↑ | 8.9 ↑ | ||
AUC | 0.846 | 0.795 | 0.934 | |||
p-value | - | - | - | |||
Mathelin et al. (2005) [2] | M/z | 4286 ↓ | 4302 ↓ | 8129 - | 8919 ↑ | 8961 ↑ |
AUC | - | - | - | - | - | |
p-value# | <0.000 | <0.001 | 0.51 | <0.02 | <0.001 | |
Li et al. (2005) | Da | ± 4300* ↑ | 8116 ↑ | 8926 ↑ | ||
Validation study [4] | AUC | - | 0.65 | 0.71 | ||
p-value | - | - | - | |||
Current study | M/z | 4276 ↓ | 4292 ↓ | 8129 - | 8941 ↓ | |
AUC | 0.716 | 0.770 | 0.510 | 0.830 | ||
p-value† | <0.0001 | <0.0001 | 0.870 | <0.0001 |
↓ = Decreased intensity in cases compared to controls, ↑ = Increased intenstiy in cases compared to controls.
M/z = Mass to Charge ratio, * Exact mass not reported, # Test used not reported, † Mann-Whitney U Test