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. Author manuscript; available in PMC: 2009 Dec 1.
Published in final edited form as: Clin Cancer Res. 2008 Dec 1;14(23):7773–7780. doi: 10.1158/1078-0432.CCR-08-1309

Figure 2. Inhibition of tumor progression by dietary silibinin in TRAMP mice with established prostate tumors.

Figure 2

The prostate tissue samples from the experiment detailed in Figure 1, were histopathologically analyzed for various stages of prostate tumor progression including prostatic intraepithelial neoplasia (PIN), well differentiated and poorly differentiated adenocarcinoma (AC) as described in Materials and Methods. The incidence of each stage is shown from 7–8 mice in each group and values in parentheses indicate percent incidence for that group. Fisher’s exact test was done to compare control group with silibinin-treated groups for each stage of PCa.