Skip to main content
. Author manuscript; available in PMC: 2010 Jan 1.
Published in final edited form as: Ann Neurol. 2009 Jan;65(1):76–82. doi: 10.1002/ana.21535

Table 3. MC1R Arg151Cys polymorphism and PD risk.

Genotype of Arg151Cys
Arg/Arg Arg/Cys Cys/Cys P-trend
Case/control 224/1015 42/160 6/10
Crude Relative risk 1 (ref) 1.19
(0.82,1.72)		 2.55
(0.91, 7.12)		 0.11
Multivariate1 1(ref) 1.23
(0.84,1.82)		 3.15
(1.06, 9.37)		 0.06
Red hair 1 P-interaction
No 1(ref) 1.25
(0.81, 1.92)		 -- 0.23
Yes 0.67
(0.19, 2.32)		 0.95
(0.30, 2.97)		 4.93
(1.50, 16.2)

Conditional logistic regressions were used to estimate relative risks.

1

Adjusted for smoking(never smoker, past smoker, or current smoker: cigarettes/d, 1-14 or ≥ 15), ethnicity (Caucasian, African-American, and Asian and others), BMI (<23, 23-24.9, 25-26.9, 27-29.9, or ≥30 kg/m2), use of non-steroid anti-inflammatory drug (yes/no), and intakes of alcohol(none, 1-4.9, 5-9.9, 10-14.9, or ≥15 g/d for women; none, 1-9.9, 10-19.9, 20-29.9, or ≥30 g/d for men), caffeine (quintiles), and lactose (quintiles).