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. 2009 Feb 23;4(2):e4552. doi: 10.1371/journal.pone.0004552

Table 1. Phenotypes of BicD phosphorylation mutants.

Mutation MS identification Phenotype
phos. non-phos.
wild type ff
S14A + ff
S14D ff
S33A + ff
S34A + ff
S36A + ff
S39A + ff
S45A + ff
multiple ff
S51A ff
S84A ff
S103A + + ff
S103D ff
S103F ff
S109A + + ff
S186A + + ff
S285A + + ff
S288A + + ff
S285A+S288A ff
S305 + + ff
S310A + + ff
S310D ff
S305A+S310A ff
A40V fs, 16 nurse cells
A40V+S103A fs, 16 nurse cells
A40V+S103D lethal with few adults, 16 nurse cells
A40V+S103F ff, few egg chambers with 16 nurse cells

Peptides containing the indicated serines were identified (+) as serine phosphorylated form (phos.) or non-phosphorylated (non-phos.), or the peptide was never identified (−). All mutants are viable, except for BicDA40V, S103D. BicDmultiple consists of the five substitutions S33A, S34N, S36N, S39A, S45A.

ff females fertile.

fs females sterile.