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Time- and concentration-dependency of IL-1β-induced IL-8 and RANTES release. A549 cells were exposed to either buffer or 1 ng/ml IL-1β for the indicated time (a) or to the indicated IL-1β concentration for 24 h (b) prior to measurement of IL-8 and RANTES release. The results are expressed as the mean ± SEM of 3 individual samples and are representative of 3 independent experiments.
