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. Author manuscript; available in PMC: 2009 Feb 11.
Published in final edited form as: J Immunol. 2008 Apr 15;180(8):5689–5698. doi: 10.4049/jimmunol.180.8.5689

Figure 6.

Figure 6

Role of miRNA-146a and miRNA-146b in the IL-1β signalling pathway. A549 cells were exposed IL-1β (1 ng/ml) and the expression of IRAK1 and TRAF6 protein (a) and mRNA (b) were detected at the indicated time points. In separate studies, A549 cells were transfected with an inhibitor or mimic of miRNA-146a, miRNA-146b or the relevant control miRNA and the effect upon IRAK1 protein expression was determined at 0 h and at 6 h following IL-1β stimulation (c). The results in panel (a) and (c) are representative of a least 3 independent experiments whilst panel (b) gives the mean ± SEM of 3 independent experiments.