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. Author manuscript; available in PMC: 2010 Jan 15.
Published in final edited form as: Biochem J. 2009 Jan 15;417(2):457–466. doi: 10.1042/BJ20080925

Figure 1. BCL11B regulates expression of IL-2 through site(s) located between −210 and −190 in addition to the US1 site.

Figure 1

(A) Schematic representation of the IL-2 promoter. (B) Ratios of Luciferase reporter assays between MSCV-BCL11B and MSCV Jurkat cells transfected with the IL-2 promoter deletion mutants. Reporter assays were conducted after treatment of the cells with PMA/ionomycin for 8 hours. The quantification represents the means of three independent experiments ± SD.