Table 3.

Effect of Ginkgo on the risk of progression to CDR = 0.5: Results of Cox proportional hazard model (n = 118)

	Model 1		Model 2		Model 3
Variables	HR	95% CI	HR	95% CI	HR	95% CI
Ginkgo (reference: placebo)	0.43	(0.17, 1.08)	0.33*	(0.12, 0.89)	0.32*	(0.11, 0.93)
Adherence level during the first 6 months			0.98	(0.96, 1.00)	0.98	(0.97, 1.00)
Age					1.10	(0.90, 1.35)
Female					0.82	(0.31, 2.14)
Years of education					0.88	(0.71, 1.09)
10-Items Center for Epidemiological Studies Depression Scale score					1.79*	(1.12, 2.87)
Having one or more ApoE4 alleles					2.35	(0.74, 7.40)
Modified Cumulative Illness Rating Scale					1.02	(0.85, 1.21)
Numbers of prescription medication taken					0.83	(0.63, 1.11)
Mini-Mental State Examination score					0.81	(0.58, 1.14)

^*Significant at p< 0.05.

CDR = Clinical Dementia Rating.