Table 4.
Model 1 |
Model 2 |
Model 3 |
||||
---|---|---|---|---|---|---|
Variables | Coefficient (SE) | p Value | Coefficient (SE) | p Value | Coefficient (SE) | p Value |
Time | -0.122* (0.045) | 0.008 | -0.163 (0.114) | 0.156 | -0.126 (0.119) | 0.291 |
GBE | -0.384 (0.303) | 0.206 | -0.299 (0.292) | 0.306 | -0.376 (0.259) | 0.147 |
Interaction of time & GBE (Time × GBE) | 0.111 (0.057) | 0.055 | 0.115* (0.057) | 0.047 | 0.103 (0.056) | 0.069 |
Adherence level during the first 6 months | 0.017* (0.005) | 0.002 | 0.012* (0.005) | 0.016 | ||
Time × adherence level during the first 6 months | 0.000 (0.001) | 0.693 | 0.000 (0.000) | 0.980 | ||
Age | -0.085 (0.053) | 0.111 | ||||
Female | 0.592* (0.249) | 0.018 | ||||
Years of education | 0.082* (0.039) | 0.035 | ||||
10-Items Center for Epidemiological Studies Depression Scale score | -0.150 (0.118) | 0.203 | ||||
Having one or more ApoE4 allele | -0.363 (0.342) | 0.288 | ||||
Modified Cumulative Illness Rating Scale | 0.080 (0.041) | 0.051 | ||||
Numbers of prescription medication taken | -0.074 (0.069) | 0.288 | ||||
Mini Mental State Examination score | 0.042* (0.083) | <0.001 |
Significant at p < 0.05.
GBE = Ginkgo biloba extract; CERAD = Consortium to Establish a Registry for Alzheimer's Disease.