Table 5.

Adverse events

Events, n (%)	GBE, n = 60	Placebo, n = 58	p Value (Fisher exact test)
Cardiac	9 (15.0)	10 (17.2)	0.80
Hypertension	1 (1.7)	0	1.00
Hematologic	1 (1.7)	2 (3.5)	0.61
Respiratory	4 (6.7)	3 (5.2)	1.00
Eyes, ears, nose, and throat	2 (3.3)	1 (1.7)	1.00
Gastrointestinal	7 (11.7)	3 (5.2)	0.32
Renal	1 (1.7)	1 (1.7)	1.00
Genitourinary	4 (6.7)	4 (6.9)	1.00
Musculoskeletal (includes fractures)	3 (5.0)	7 (12.1)	0.20
Falls	4 (6.7)	7 (12.1)	0.35
Stroke/TIA	7 (11.7)	0	0.01*
Endocrine-metabolic	0	2 (3.5)	0.23
Malignancy	1 (1.7)	4 (6.7)	0.20
Others (dizziness, fatigue, vertigo, blurred vision)	2 (3.3)	2 (5.2)	1.00
Total no. of events reported	46	46	0.82
Total no. of subjects with adverse events†	29 (48.3)	31 (53.5)	0.58

^*Significant at p < 0.05.

^†Due to multiple events reported per subject, the total number of subjects with adverse events is smaller than the total number of events reported.

GBE = Ginkgo biloba extract.