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. Author manuscript; available in PMC: 2009 Feb 11.
Published in final edited form as: Biochem Pharmacol. 2006 Jan 31;71(6):806–817. doi: 10.1016/j.bcp.2005.12.028

Fig. 4.

Fig. 4

Berberine inhibited SMC regrowth and migration after mechanical injury. SMCs were grown to 80% confluency. We created a linear injury line at center of cultured monolayer by scraping with a sterile pipette tip. The cells were then maintained in 1% FBS-DMEM with various concentrations of berberine for 3 days. (A) Cell morphology was microphotographed. Magnification: 100×. (B) The closure of denuded area was calculated as described in Section 2.