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. 2008 Sep 8;107(2):416–426. doi: 10.1093/toxsci/kfn192

FIG. 5.

FIG. 5.

Arsenite sensitivity of X-chromosomal deficiency lines. (A) Arsenite dose-response assay on parental w1118/Binsinscy strain to identify an experimental concentration threshold for testing toxic effects on Df lines. We chose to use 0.25mM arsenite for the sensitivity assays. Each bar represents the relative viability of emerging w1118/Binsinscy adults exposed to the specified concentration of arsenite-supplemented food when compared to emerging w1118/Binsinscy adults exposed to nonsupplemented food. *p < 0.01, **p < 0.005. (B) Viability ratio of various Df lines compared to that of the isogenic parental strain (w1118/Binsinscy) tested on 0.25mM arsenite-supplemented food. *p < 0.05, **p < 0.01. (C) Deficiency #11 encompasses a region containing five annotated genes: CG6835 and CG32495 encode the enzyme GS, CG6788 and CG32496 are genes encoding cell adhesion molecules, and CG7772 encodes a protein with carbonate dehydratase activity.