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(a) Metabolism of glyoxal and MG by the glyoxalase system. (b) Metabolism of 3DG by 3-deoxyglucosone reductase, an AKRd. (c) Metabolism of 3DG by 3-deoxyglucosone dehydrogenase. (d, e) Repair of early glycated proteins by Amadoriase and fructosamine-3-phosphokinase.
