Fig. 4.
Over-expression of the basic helix-loop-helix proteins NeuroD1 or Mash1 are sufficient to increase expression of a 4X E-box 3 multimer reporter gene. αT3-1 and LβT2 cells were transiently transfected with E-box 3 multimer reporter gene and expression vectors for NeuroD1,Mash1, or empty expression vector, as a control.