Table 6.
Validation experiment
| Estimated based on (X = S1, S2) | ||||
| Experiment | X | X with 15% | X with 30% | |
| S1 | 76,24 | - | 79,21 | 77,23 |
| S1 with 15% | 82,18 | 80,20 | - | 81,19 |
| S1 with 30% | 84,16 | 83,17 | 85,15 | - |
| S1 | 60,29,11 | - | 72,20,8 | 70,21,9 |
| S1 with 15% | 76,17,7 | 66,25,9 | - | 75,18,7 |
| S1 with 30% | 79,15,6 | 72,20,8 | 80,14,6 | - |
| S2 | 62,24,14 | - | 49,33,18 | 50,31,19 |
| S2 with 15% | 57,28,15 | 68,20,12 | - | 57,27,16 |
| S2 with 30% | 65,22,13 | 73,17,10 | 65,23,12 | - |
In the "Experiment" column, the estimated subpopulation percentages from the 6 experiments are shown: Two pure tumor samples (S1 and S2), and four samples with tumor mixed with 15 or 30% normal cells. The best fit for S1 is three subpopulations, whereas it is two for "S1 with 15%" and "S1 with 30%"; therefore we show results for both two and three subpopulations to facilitate comparison. The remaining three columns contain percentages estimated from the Experiment column; e.g. to estimate the percentages of the sample with 85% malignant cells and 15% normal cells ("S2 with 15%") from the sample S2 do (0.62·85 + 15, 0.24·85, 0.14·85) = (68, 20, 12).