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. 2009 Jan 9;10:12. doi: 10.1186/1471-2105-10-12

Table 6.

Validation experiment

Estimated based on (X = S1, S2)
Experiment X X with 15% X with 30%
S1 76,24 - 79,21 77,23
S1 with 15% 82,18 80,20 - 81,19
S1 with 30% 84,16 83,17 85,15 -
S1 60,29,11 - 72,20,8 70,21,9
S1 with 15% 76,17,7 66,25,9 - 75,18,7
S1 with 30% 79,15,6 72,20,8 80,14,6 -
S2 62,24,14 - 49,33,18 50,31,19
S2 with 15% 57,28,15 68,20,12 - 57,27,16
S2 with 30% 65,22,13 73,17,10 65,23,12 -

In the "Experiment" column, the estimated subpopulation percentages from the 6 experiments are shown: Two pure tumor samples (S1 and S2), and four samples with tumor mixed with 15 or 30% normal cells. The best fit for S1 is three subpopulations, whereas it is two for "S1 with 15%" and "S1 with 30%"; therefore we show results for both two and three subpopulations to facilitate comparison. The remaining three columns contain percentages estimated from the Experiment column; e.g. to estimate the percentages of the sample with 85% malignant cells and 15% normal cells ("S2 with 15%") from the sample S2 do (0.62·85 + 15, 0.24·85, 0.14·85) = (68, 20, 12).