Table 2.
MIPS functional categories specifically associated with combinatorial effects
Enrichment p-values | ||||
MIPS category | single effects | comb. effect | ||
Acetate | Ethanol | both | Acetate | Ethanol | |
METABOLISM | 0.065 | 0.077 | 1 | 7.8·10-18 |
metabolism of glutamate | 1 | 0.048 | 1 | 1.4·10-6 |
C-compound and carbohydrate metabolism | 0.027 | 0.082 | 1 | 1.4·10-22 |
C-compound and carbohydrate utilization | 0.02 | 0.043 | 1 | 1.3·10-17 |
C-compound, carbohydrate catabolism | 0.2 | 1 | 1 | 8·10-13 |
sugar, glucoside, polyol and carboxylate catabolism | 0.44 | 1 | 1 | 9.3·10-11 |
ENERGY | 0.013 | 1 | 1 | 1·10-17 |
glycolysis and gluconeogenesis | 1 | 1 | 1 | 3.8·10-9 |
tricarboxylic-acid pathway | 1 | 1 | 1 | 2.2·10-11 |
Phosphorus | Sulfur | both | Phosphorus | Sulfur | |
transcriptional control | 0.13 | 0.017 | 1 | 4.3·10-8 |
RNA processing | 0.86 | 0.32 | 1 | 1.5·10-6 |
rRNA processing | 0.5 | 0.83 | 1 | 3.3·10-6 |
The combinatorial effects 'carbon source acetate OR ethanol' and 'Limiting element phosphorus OR sulfur' are specifically associated to the listed MIPS functional categories. P-values of the enrichment of genes within these categories that are affected by the combinatorial effect are given in the rightmost column. Also, enrichment p-values of genes affected by each and by both of the single effects that constitute this combinatorial effect are given.