Table 2. Donepezil had minimal effect on fixation stability during passive viewing of the checkerboard stimulus annulus.

Subjects #2 - #5 from the fMRI portion of this study repeated the passive viewing experiment in a behavioral testing room. The pharmacological procedures and visual stimulus were identical to those used in the fMRI experiments. Time series of horizontal (x) and vertical (y) position were recorded, and the standard deviation (SD_x and SD_y) over each 5-minute run was computed. Standard deviations are presented in units of degrees of visual angle. In addition, a circular fixation window of one degree radius was defined, and the percent of viewing time during which the eye position was within this window was measured. None of the three eye position measures showed significant differences between placebo and donepezil sessions (paired t-test).

	placebo			donepezil
subject #	SDx (deg)	SDy (deg)	% fix wind.	SDx (deg)	SDy (deg)	% fix wind.
2	0.34	0.29	78	0.59	0.89	56
3	0.26	0.32	98	0.34	0.39	89
4	0.38	0.35	94	0.34	0.27	97
5	0.66	0.56	91	0.63	0.42	93
group	0.41	0.38	90	0.47	0.49	84