Table 1. Immunohistochemistry localisation of the various components of the endocannabinoid system in the human ovary.
Structure | Cell type | CB1 | CB2 | FAAH | NAPE-PLD |
Primordial Follicle | oocyte | + | ++ | − | −/+ |
granulosa | + | ++ | − | + | |
Primary Follicle | oocyte | + | ++ | − | − |
granulosa | + | + | − | − | |
Secondary Follicle | oocyte | + | ++ | − | − |
granulosa | + | + | + | ++ | |
theca | + | + | ++ | ++ | |
Tertiary Follicle | oocyte | − | ++ | − | − |
granulosa | ++ | + | −/+ | −/++ | |
theca | + | + | ++ | ++ | |
Corpus luteum | ++ | + | + | ++ | |
Corpus albicans | + | + | − | + |
Scoring system (−) = staining absent; (+) = staining visible; (++) = strong staining.