Table 4.

Serial Changes in Diastolic Parameters

Diastolic Function	LS	LSG	HS	HSG	HSH
E/A
0 w	2.7 ± 0.2	2.7 ± 0.3	2.6 ± 0.2	2.6 ± 0.3	2.4 ± 0.3
8 w	2.9 ± 0.1	2.8 ± 0.3	2.0 ± 0.3*	2.4 ± 0.2†	2.2 ± 0.2*
18 w	2.6 ± 0.3	2.5 ± 0.1	6.2 ± 0.3*	3.8 ± 0.1†	5.8 ± 0.3*
E Dec time
0 w	43.6 ± 3	44.0 ± 4	43.3 ± 6	43.2 ± 5	43.1 ± 4
8 w	42.1 ± 3	41.7 ± 5	48.3 ± 3*	45.7 ± 4	47.2 ± 4*
18 w	44.0 ± 2	43.0 ± 4	34.2 ± 3*	39.9 ± 3	35.6 ± 3*
IVRT
0 w	17.7 ± 3	17.3 ± 2	18.8 ± 2	16.7 ± 1	18.1 ± 3
8 w	18.3 ± 2	18.1 ± 3	20.5 ± 2	20.1 ± 3	19.5 ± 2
18 w	21.1 ± 2	20.4 ± 3	31.5 ± 3*	24.3 ± 1†	30.1 ± 3*

Notes: Echocardiography measures at 0 weeks of diet (baseline), 8 weeks of diet, and 18 weeks of diet. Data presented are means ± standard error of the mean; n = 12 per group.

E/A = E wave to A wave; E Dec t = E wave deceleration time (in ms); IVRT = isovolumetric relaxation time (in ms); LS = low-salt diet; LSG, low salt + grape powder diet; HS = high-salt diet; HSG = high salt + grape powder diet; HSH = high salt + vasodilator hydralazine diet.

^*At least p < .05 vs LS, LSG.

^†p < .05 vs LS, LSG, HS, HSH.