Table 6.

Changes in Organ Weight and Cardiac Fibrosis

	LS	LSG	HS	HSG	HSH
Heart W/TL	0.34 ± 0.01	0.33 ± 0.02	0.42 ± 0.1*	0.32 ± 0.01†	0.43 ± 0.3†
Kidney W/TL	0.71 ± 0.04	0.65 ± 0.04	0.98 ± 0.05*	0.82 ± 0.04†	0.83 ± 0.06†
Lung W/TL	0.42 ± 0.04	0.40 ± 0.04	0.54 ± 0.06	0.43 ± 0.05	0.52 ± 0.04
Cardiac hydroxyproline	5.2 ± 0.3	5.1 ± 0.2	9.2 ± 0.2*	7.4 ± 0.3†	9.1 ± 0.3*
Cardiac perivascular area fibrosis	1.19 ± 0.04	1.17 ± 0.02	1.45 ± 0.1*	1.3 ± 0.03†	1.40 ± 0.*

Notes: HW (g heart weight), KW (g kidney weight), and LW (g lung weight) are relative to tibial length (TL) in centimeters. Perivascular area fibrosis is expressed as microns squared. Hydroxyproline is expressed as milligrams per milligrams of total protein. Data are presented as means ± standard error of the mean; n = 12 per group.

LS = low-salt diet; LSG = low salt + grape powder diet; HS = high-salt diet; HSG = high salt + grape powder diet; HSH = high salt + vasodilator hydralazine diet.

^*At least p < .05 vs LS and LSG.

^†p < .05 vs LS, LSG, HS.