Table 2.
Comparison of plasma VWF levels of parental strains and 205 F2 progeny grouped by genotype
| n | VWF level, % ± SD | |
|---|---|---|
| Parental strains | ||
| RIIIS/J | 14 | 5 ± 1 |
| (RIIIS/J × CASA/Rk)F1 | 30 | 13 ± 5 |
| CASA/Rk | 24 | 100 ± 33 |
| F2 progeny | ||
| Homozygous RIIIS/J at D11Mit54 | 52 | 11 ± 7 |
| Heterozygous at D11Mit54 | 98 | 14 ± 7 |
| Homozygous CASA/Rk at D11Mit54 | 55 | 49 ± 21 |
VWF levels of mice were determined by ELISA. The average VWF level of parental CASA/Rk mice is arbitrarily defined as 100%. n, number of mice. F2 progeny are grouped by genotype at D11Mit54 near the Mvwf locus.