FIGURE 5.

Summary of the genome-wide transcriptional effects of TBP Y185C and TBP F207L. A, Venn diagram depicting overlap between significantly misregulated genes (>99% confidence) in mot1-14, TBP Y185C, and TBP F207L strain data sets. B, Venn diagram showing the number of Mot1-dependent genes whose expression was restored to WT levels by TBP Y185C or TBP F207L and the overlap between the two. For panels A and B the area of the overlapping region is not proportional to the number of genes contained within that category. C, pie charts breaking down the genes in panel B according to whether they were originally Mot1-activated or Mot1-repressed and by-fold change. The numbers of genes affected less than 2-fold are shown in light blue and light red, and the numbers of genes affected greater than 2-fold are shown in dark blue and dark red, respectively. The slice of the pie is proportional to the number of genes contained within that category.