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. 2009 Feb 13;284(7):4292–4299. doi: 10.1074/jbc.M807503200

FIGURE 5.

FIGURE 5.

Altered hair cycling in Dgat1-/- mice. a, schematic of the first two postnatal hair cycles in Dgat1-/- and wild-type mice (P44, n = 6/genotype; P63, n = 5/genotype; n = 3/genotype at all other time points). A, anagen (black); C, catagen (black gradient); T, telogen (white). b, precocious onset of second anagen in Dgat1-/- mice. Dgat1-/- and wild-type mice were shaved on P51 and photographed at various time points thereafter. Precocious anagen onset is evident in Dgat1-/- mice by the appearance of new hair at P63 and complete regrowth of hair by P76 (n = 5/genotype). c, retinoid deprivation modulates the onset of the second anagen phase in Dgat1-/- mice. Schematic time line depicting the onset of the second postnatal anagen phase in five retinoid-depleted Dgat1-/- mice compared with the average age of onset of second anagen in chow-fed Dgat1-/- and wild-type mice (32). T, telogen (white bar); A, anagen (black bar). RD, retinoid-deficient; RS, retinoid-sufficient.