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Relationship between tissue (muscle homogenate) activities of cytochrome c oxidase and citrate synthase and age. Male and female subjects are presented as one group for each enzyme. Both activities of cytochrome c oxidase (y = −0.72x + 142.8; r2 = 0.22) and citrate synthase (y = −1.01x + 232.6; r2 = 0.20) decreased significantly with increasing age (respectively, P < 0.0017 and P < 0.0033).
