Figure 3.

Predicted amino acid sequence alignment of 31 amino acids (in single-letter code) representing HVR1 of the E2 gene, spanning map position 384–414, of 104 molecular clones obtained from HCV, strain H77, which was used for inoculation. The sequence obtained by direct sequencing is indicated at the top for comparison. The standard viral stock used for all the inocula (H77) was obtained from patient H during the acute phase of posttransfusion NANB hepatitis (31). The remaining sequence of the 191 amino acids spanning map position 318–508, which is not shown, is available upon request.