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NO+ donor compounds inhibit synaptic activity of mass cultures in a dose-dependent manner. (A) Dose-dependent inhibitory effect of NTG on the frequency of postsynaptic currents, normalized to control conditions. Data points represent means ± SEM (for n = 15 cortical neurons in mass culture). (B) Dose-dependent inhibitory effect of SNOC on the frequency of postsynaptic currents (for n = 11 neurons).
