TABLE 2.

Mortality rates and hazard ratios and 95% confidence intervals of mortality according to the combination of BMI and smoking ¹,²

	BMI
	<18.5				18.5–<23.5				23.5–<25				25–<30				30–<35				≥35

Smoking status	Rate³	HR	95% CI		Rate³	HR	95% CI		Rate³	HR	95% CI		Rate³	HR	95% CI		Rate³	HR	95% CI		Rate³	HR	95% CI
MEN
Never Former	1664	2.11	1.55	2.88	785	1.08	0.96	1.21	741	1.00			844	1.11⁴	1.01	1.22	1137	1.41	1.26	1.59	2055	2.44	2.10	2.82
≥10 yrs Former	1409	2.96	2.18	4.00	1163	2.45	2.16	2.79	1038	2.15	1.89	2.45	1148	2.22	1.97	2.50	1526	2.67	2.35	3.02	2132	3.51	3.05	4.05
<10 yrs	5820	9.64	7.01	13.26	2943	5.46	4.74	6.30	2185	4.09	3.53	4.74	2155	3.92	3.46	4.44	2244	3.79	3.30	4.35	2990	5.00	4.21	5.93
Current	4910	8.36	6.27	11.15	3424	6.48	5.66	7.41	3179	6.15	5.34	7.08	2748	5.21	4.58	5.94	3171	5.87	5.05	6.83	4522	8.13	6.61	10.01
WOMEN
Never Former	699	1.51	1.08	2.13	517	1.17	1.02	1.35	454	1.00			531	1.14³	0.99	1.31	650	1.33	1.13	1.56	1117	2.18	1.84	2.58
≥10 yrs Former	878	3.01	1.85	4.89	612	2.09	1.52	2.87	563	1.85	1.33	2.57	712	2.20	1.61	3.01	936	2.71	1.96	3.75	1446	3.86	2.77	5.38
<10 yrs	4064	11.98	7.88	18.22	1523	4.66	3.39	6.40	986	2.91	2.06	4.11	1218	3.41	2.48	4.69	1482	3.88	2.78	5.41	2141	5.09	3.59	7.23
Current	3124	9.41	6.54	13.53	1923	5.86	4.28	8.02	1759	5.35	3.85	7.43	1807	5.11	3.71	7.03	2113	5.85	4.14	8.25	2398	6.61	4.48	9.76

Cox proportional hazard models adjusted for age, race, education, smoking intensity, physical activity, and alcohol consumption

The interaction between the combination of BMI and smoking and sex were statistically significant (p<0.01)

Age standardized mortality rates per 100,000 person years, standardized to the age distribution of the cohort in men and women

⁴

Hazard ratios among never smokers when we further split up the overweight group. Men: BMI 25–<27.5: HR: 1.04, 95%CI: 0.94, 1.15, BMI 27.5–<30: HR: 1.24, 95%CI: 1.11, 1.39; Women: BMI 25–<27.5: HR: 1.09, 95%CI: 0.94, 1.27; BMI 27.5–<30: HR: 1.23, 95%CI: 1.04, 1.45