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. Author manuscript; available in PMC: 2009 May 1.
Published in final edited form as: Mol Cancer Res. 2008 May;6(5):795–807. doi: 10.1158/1541-7786.MCR-07-2097

Table 2.

nSMase3 Overexpression Sensitizes DLD1 Cells to Adriamycin-Induced Apoptosis

Stable Cell Line Colonies per Plate
Experiment 1
 Experiment 2
 Experiment 3
Control Adriamycin Control Adriamycin Control Adriamycin
Vector 2,430 168 2,430 464 3,170 636
nSMase3 7 2,410 88 2,790 400 3,010 148
nSMase3 35 2,920 6 2,220 57 2,750 60

NOTE: DLD1 human colon cancer cells stably expressing pcDNA3.1-Myc or pcDNA3.1-Myc-nSMase3 were treated with 40 nmol/L Adriamycin for 48 h. Cells were then cultured in medium without Adriamycin for 10 to 14 d and the numbers of colonies were counted.