Table 1.
Body weight and blood glucose values in the experimental groups: control (N=21), control + vapiprost (1 mg/kg/day; N=7), streptozotocin (STZ; N=20), and STZ + vapiprost (1 mg/kg/day; N=8). Glucose levels are reported as median values.
| Group | Day of injection | Day 6 after injection | Week 4 after injection | ||||
|---|---|---|---|---|---|---|---|
| Control | STZ | Control | STZ | Control | STZ | ||
| Weight (g) | 4 week | 25.0 ± 0.4 | 25.1 ± 0.3 | 26.0 ± 0.4 | 20.6 ± 0.6 *** | ||
| 4 week + vapiprost | 26.1 ± 0.4 | 26.4 ± 0.4 | 27.3 ± 0.3 | 22.2 ± 1.1 *** | |||
| Glucose (mg/dl) | 4 week | 182 | 509 | 212 | >600 | ||
| 4 week + vapiprost | 170 | 566 | 190 | >600 | |||
p<0.001 vs respective day of Control, and p<0.001 vs STZ day of injection.