Figure 4.
Effect of normoxic and hypoxic PO2 on carotid body (CB) chemoafferent discharge in CB from sham, chronic heart failure (CHF), and CHF treated with either adenoviral copper/zinc superoxide dismutase (Ad CuZnSOD) or Ad Empty. (A) Representative recording of CB chemoreceptor afferent discharge. (B) CB chemoafferent response to hypoxia. DF, discharge frequency; AP, action potential. Data are mean ± SEM. n = 6 each group. *P < 0.05 compared with sham group, #P < 0.05 compared with CHF + Ad CuZnSOD group.