Table 1.
Body weight, ventricular weight and cardiac function in sham and CHF rabbits
| n | BW (kg) | LVW/BW (g/kg) | LVEDD (mm) | LVESD (mm) | FS (%) | EF (%) | |
|---|---|---|---|---|---|---|---|
| Sham | 16 | 3.6 ± 0.1 | 1.4 ± 0.1 | 13.8 ± 0.1 | 9.3 ± 0.3 | 39.3 ± 0.4 | 75.3 ± 1.2 |
| CHF | 24 | 3.8 ± 0.1 | 1.9 ± 0.1* | 16.9 ± 0.5* | 12.0 ± 0.4* | 20.2 ± 2.4* | 44.8 ± 0.7* |
| CHF + Ad Empty | 16 | 3.7 ± 0.1 | 1.9 ± 0.1* | 17.1 ± 0.5* | 11.9 ± 0.4* | 21.5 ± 2.2* | 45.2 ± 0.6* |
| CHF + Ad CuZnSOD | 16 | 3.8 ± 0.1 | 1.9 ± 0.1* | 17.2 ± 0.5* | 12.1 ± 0.4* | 20.1 ± 2.2* | 44.0 ± 0.6* |
Data are mean ± SEM; BW, body weight; LVW, left ventricular weight; LVEDD, left ventricular end diastolic diameter; LVESD, left ventricular end systolic diameter; FS, fractional shortening; EF, ejection fraction. *P < 0.05 compared with sham.