Figure 1. The MIG-15 NIK kinase.
MIG-15 contains a STE20 class serine/threonine kinase domain, a proline rich domain (PRD), and a citron/NIK homology (CNH) domain. The effects of the mu327, rh148, mu342, rh326, and rh80 mutations are shown. qid-7(mu327) was a G to A missense mutation at position 89 in the mig-15 open reading frame, resulting in glycine 30 to glutamic acid change. qid-8(mu342) was a G to A missense mutation at position 667, resulting in glutamic acid 223 to lysine change.