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. Author manuscript; available in PMC: 2009 Dec 12.
Published in final edited form as: Cell. 2008 Dec 12;135(6):1130–1142. doi: 10.1016/j.cell.2008.10.035

Figure 3. Frequencies of Breakpoints at CpG in Various Chromosomal Rearrangements.

Figure 3

Percentages of breakpoints at CpGs are plotted for various chromosomal rearrangements, organized by cell lineage and stage of development when the rearrangement occurs. Frequencies for pro-B/pre-B rearrangements far exceed those from other lineages and stages. Frequencies at various distance intervals from CpG and CAC, along with comparison to random breakpoint distributions, are shown in the supplementary materials (Suppl. Fig. 3). Statistical analysis of this phenomenon is described in the text and supplementary text.