Table 2.
Age and sex-adjusted associations of adiponectin with selected cardiovascular risk factors in those with and without prevalent CHD: the Rancho Bernardo Study.
| No CHD (N=1352) | CHD (N=161) | |
|---|---|---|
| Cardiovascular risk factors | R† | R† |
| Age | .32*** | .32*** |
| Body mass index | −.29*** | −.23** |
| Waist girth | −.30*** | −.26*** |
| Waist hip ratio | −.26*** | −.21** |
| Systolic blood pressure | −.02 | −.11 |
| Diastolic blood pressure | −.03 | −.09 |
| Pulse pressure | −.01 | −.08 |
| Total cholesterol | .01 | .02 |
| LDL cholesterol | −.05 | .02 |
| HDL cholesterol‡ | .43*** | .52*** |
| Triglycerides‡ | −.35*** | −.47*** |
| Fasting plasma glucose | −.17*** | −.18* |
| Creatinine | −.03 | −.06 |
| Mean† | Mean† | |
| Lifestyle variables (yes/no) | ||
| Current smoking | 12.2/11.9 | 12.1/10.4 |
| Alcohol, 1+ dks/dy | 12.7/11.4*** | 11.7/9.6* |
| Exercise, 3+ x/wk | 11.9/12.1 | 10.7/10.2 |
| Concomitant conditions (yes/no) | ||
| Diabetes | 9.6/12.4*** | 9.7/10.9 |
| Metabolic syndrome | 8.5/12.9*** | 7.1/11.9*** |
| Hypertension | 11.8/12.5 | 10.3/11.3 |
| Weight loss ≥ 10 lbs (yes/no) | 13.9/11.5*** | 13.8/9.6*** |
| Family history of MI§ (yes/no) | 12.0/11.9 | 11.8/10.5 |
| Aspirin use (yes/no) | 12.4/11.9 | 10.7/10.4 |
*
p ≤ 0.05,
**
p ≤ 0.01,
***
p ≤ 0.001 versus adiponectin
†
values are Pearson partial correlation coefficients for continuous variables and adjusted geometric means for categorical variables.
‡
log10-transformed for analysis; values are geometric means.
§
MI, myocardial infarction