Table 3.
Age and sex adjusted odds ratios (95% confidence intervals) for prevalent CHD (N=161) according to levels of adiponectin in 1513 older men and postmenopausal women: the Rancho Bernardo Study.
| Model 1† | Model 2‡ | Model 3§ | |||||
|---|---|---|---|---|---|---|---|
| HR | 95% CI | HR | 95% CI | HR | 95% CI | ||
| Per quintile | (# cases) | ||||||
| 1 | (38) | 1 | 1 | 1 | |||
| 2 | (29) | 0.64 | 0.38, 1.08 | 0.58 | 0.34, 1.00 | 0.72 | 0.42, 1.26 |
| 3 | (33) | 0.66 | 0.40, 1.11 | 0.64 | 0.38, 1.07 | 0.87 | 0.50, 1.49 |
| 4 | (27) | 0.53 | 0.31, 0.90 | 0.47 | 0.27, 0.82 | 0.71 | 0.40, 1.28 |
| 5 | (34) | 0.56 | 0.33, 0.94 | 0.45 | 0.26, 0.79 | 0.83 | 0.45, 1.55 |
| p-for trend | 0.025 | 0.006 | .56 | ||||
| Per unit increase in log | 0.49* | 0.24, 0.98 | 0.39* | 0.19, 0.81 | 0.96 | 0.41, 2.25 | |
| Per SD in log increase | 0.84* | 0.71, 0.99 | 0.80* | 0.67, 0.95 | 0.98 | 0.80, 1.21 | |
| -excluding diabetes # | 0.81* | 0.67, 0.99 | 0.78* | 0.64, 0.95 | 0.92 | 0.73, 1.15 | |
| -excluding MS†† | 0.90 | 0.73, 1.10 | 0.86 | 0.69, 1.06 | 1.00 | 0.78, 1.28 | |
*
p ≤ 0.05
†
Model 1: adjusted for age and sex
‡
Model 2: adjusted for age, sex, and waist girth
§
Model 3: adjusted for Model 2 variables plus HDL cholesterol, triglycerides, and fasting plasma glucose
#
Excluding 230 participants with diabetes, 38 with CHD
††
Excluding 271 participants with MS, the metabolic syndrome; 37 with CHD