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Oxidative decomposition of the Amadori product leads to the formation of a wide range of reactive carbonyl and dicarbonyl compounds. These intermediate glycation products (IGPs) include glyoxal, methylglyoxal, glycolaldehyde, 3-deoxyglucosone, 1-deoxyglucosone, 4,5-dioxopentose, and 5,6-dioxohexose. These IGPs can also be produced by autoxidation of glucose or, in the case of glyoxal and methylglyoxal, by peroxidation of lipids.
