Fig. 3.

Stronger IFN, inflammatory, and innate immune transcriptional induction in the H5N1 group. Heat maps were generated with genes of interest after performing a 1-way ANOVA (P ≤ 0.01, Benjamini-Hochberg FDR) with statistical cut-off criteria of a 5-fold change in at least 2 experiments (P ≤ 0.01). Up-regulation relative to the reference pool is in red, down-regulation in green, and lack or statistically nonsignificant regulation in the darker shades of these colors. *, this transcriptional profile is from a non-lesion area of the animal euthanized on day 7, since tissues from H5N1 day 6 death were not suitable for RNA isolation.