Fig. 4.

Sustained inflammatory response in H5N1 infected macaques. (A) Mac 387 staining (10×) of lung sections with representative pathology and infection from each experimental group on days 1, 2, 4, and 7. This image illustrates the prolonged and more severe degree of granulocyte and macrophage infiltration in the H5N1 group and the intermediate phenotype of the 1918HANANS group for Mac387. (B) H&E staining (20×) of terminal bronchioles in the H5N1 and 1918HANA group on day 1, showing the severe damage to bronchiolar epithelium and severe infiltration of immune cells in the lumen of H5N1 animals.