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. Author manuscript; available in PMC: 2009 Oct 28.

Published in final edited form as: Neuroscience. 2008 Aug 27;156(4):1005–1016. doi: 10.1016/j.neuroscience.2008.08.030

Table 3.

Plasma Antipsychotic Levels

Test Group	Dose/24 hr	Compound Measured	Plasma Concentration (ng/mL )± S.E.M. N=4–6			Estimated Human Therapeutic Plasma Range (ng/mL)^*
			45 Days	90 days	180 days
chlorpromazine	10.0 mg/kg	chlorpromazine	6.2 ± 2.1	15.4 ± 2.9	11.9 ± 2.8	25–350 (or unknown)
olanzapine	10.0 mg/kg	olanzapine	23.7 ± 8.9	31.0 ± 9.9	22.6 ± 7.5	9.0–80.0

^*

Estimated human therapeutic plasma ranges listed are based on Curry et al., 1970; Baldessarini et al., 1988; Chetty et al., 1996; Perry et al., 2001; Rao et al., 2001; Gex-Fabry-Fabry et al., 2003.