Figure 3. OAS1 rs10774671 AA genotype frequency is elevated in both symptomatic and asymptomatic WNV-seropositive subjects.
(A) A plot of the OAS1 rs10774671 AA genotypic frequency in all WNV-positive samples (n = 501), WNV-positive samples from individuals who remained symptom-free (asymptomatic; n = 170), and WNV-positive samples from individuals who experienced symptomatic disease (n = 331). Symptomatic WNV-seropositive cases were further examined based on the CDC-defined clinical definition of WNF (n = 119) or WNND (n = 164). Black bar and the dotted line indicate the genotypic frequency of the control population (n = 552). (B) A similar analysis was performed for the OASL rs3213545 TT genotype.