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. Author manuscript; available in PMC: 2009 Dec 12.
Published in final edited form as: Neurosci Lett. 2008 Oct 7;447(2-3):175–178. doi: 10.1016/j.neulet.2008.10.008

Figure 4.

Figure 4

Changes in percent of bites occurring in clusters following dental drilling. Pulp exposure caused a significant (*) reduction at 4 and 24 hours post exposure (P= 0.043 and 0.046 respectively). Administration of 5 mg/kg s.c. morphine attenuated this effect to baseline values; this was significantly reversed by i.p. 1 mg/kg naloxone. In the superficially drilled group, a reduction (not significant ) was seen at 4 hours post-drilling that returned to normal by 24 hours post drilling. In the anesthesia only group no changes from baseline values were noted at all time point relative to baseline. Morphine was administered to 5 of the 12 rats that had pulpal exposure 24 houres following the pulp exposure, the remaining 7 rats were tested for the 48 h time point.